Clinical Wounds Solutions
Clinical Wound Solutions


  • Collagen is a natural biomaterial that has unique properties and has been used for health care since the ancient Egyptian civilization. It is the most abundant protein found in the body. There are 13 different types of collagen. Types 1, 3 and 5 are specific for skin.
  • Chains of amino acids make up collagen. These chains form collagen molecules which in turn, from fibrils. These fibrils produce fibers. Bundled fibers lead to body tissue formation.
  • Distribution and orientation of collagen reflects the function of the tissue in which it is found. For example, it is collagen that transmits tension in tendon, lends structural support in skin and bone and limits expansion in arteries.
  • Collagen plays an integral part during each phase of wound healing and is an excellent hemostatic agent. It absorbs 40 - 60 times its weight in fluid.
  • The most abundant and well characterized collagen is type 1 extracted from bovine (cow) hide. Other sources include porcine (pig), chicken tendon, bovine tendon, etc.
  • When applied to a wound, collagen initially acts as a hemostatic agent. Continued application seems to aid and hasten the body's own repair mechanisms.
    Product Name Manufacturer
    Fibracol Plus Collagen 2X2 JOHNSON & JOHNSON®
    Fibracol Plus Collagen 4X4 3/8 JOHNSON & JOHNSON®
    Prisma Matrix Dressing, 4.34 JOHNSON & JOHNSON®
    Promogran 4.34 JOHNSON & JOHNSON®
    Medifil Particles Collagen 5ml MEDLINE®
    Puracol Collagen 4 X 4.25" MEDLINE®
    Puracol Collagen 2X2 MEDLINE®
    Cellerate powder 1gr WOUND CARE INNOVATIONS, LLC®

Please call with any questions or concerns regarding use or application process as it applies to a specific wound or to a specific wound location, or with any other questions or concerns about what may be utilized in a particular situation.